The Handshakin site is run by Matt (Handshakin) Holmes. He earned an MBA in 2012 and is the founder of Holmes Real Estate Group, a real estate investment company that, in the words of the bio on his website, "funds his passion for helping startups and entrepreneurs."
By the way, you don't have to be in Colorado to learn from the resources of the Handshakin community. There is a great (and free!) library of videos on their website. These videos feature interviews with successful business owners in Colorado. So far, the videos include people from a variety of industries, from a physician/investor to an artist/entrepreneur.
If you're local to the Denver area, you can join the Startup Denver Meetup to connect in person with other businesspeople. Other local events include mentorship, apprenticeship, and internship programs to help you meet people who have found success as independent business owners.
For business tips every day and to find out about the latest local Handshakin events, you can like the Handshakin Holmes Facebook page.